Department of Biomolecular Chemistry, UW School of Medicine and Public Health

Current Members

Keck Lab Spring 2024

Left to right, top to bottom: Zoe, Emma, Haley, Rachel, Jim, Molly, Sarah, Andrew, Alex

Principal Investigator

James L. Keck

Professor
Department of Biomolecular Chemistry
Associate Dean for Basic Sciences (UW SMPH)

Affiliated with:

Graduate Students, Post Docs, & Lab Affiliates

Sarah McMillan

Postdoctoral Fellow

Research Bio: Studying the role of the single stranded DNA binding protein (SSB) in single strand gap repair. Additionally, characterizing the role of a highly conserved DNA repair protein, RarA, in holiday junction resolution.

Haley Deorio

4th Year IPiB Student

Research Bio: My research focuses on understanding the regulatory mechanisms of restarting failed DNA replication reactions in E. coli. By using single-molecule, biochemical, and structural approaches, my work will specifically characterize the PriA-PriB replication restart pathway.

Molly Dolan

2nd Year IPiB Student

Research Bio: My research examines how DNA replication is restarted after the replication machinery disassociates from the DNA in gram-positive bacteria. I use biochemical assays and Cryo-EM to characterize the interaction between two major proteins in the DNA replication restart pathway.

Zoe Wetmore

2nd Year IPiB Student

Research Bio: My research in the Keck lab focuses on the process of postreplication ssDNA gap repair in E. coli. I want to further elucidate how the proteins involved in initiating ssDNA gap repair interact with each other by using different biochemical and structural approaches.

Alex Duckworth (Lab Affiliate)

Postdoctoral Fellow (Tim Grant)

Research Bio:

 

Peter Ducos (Lab Affiliate)

5th Year Biophysics Student (Tim Grant)

Research Bio:

Undergraduate Students

Jadon Tan

Senior at UW Madison

Staff

Kenneth Satyshur

Associate Scientist